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Position Title:
Postdoctoral Research Associate

Appointment Type:
Post Doc/Trainee

Job Description:
Summary of Duties and Responsibilities:

The position involves three areas of focus:
1) Research (70%) - The research part mainly involves conducting independent and collaborative projects that use biochemical, biophysical, and structural methods to study regulatory mechanisms of protein complexes central to membrane signaling and the actin cytoskeleton. Specifically, the research activities include protein expression from both bacterial and insect cell cultures, purification and reconstitution of large protein complexes using a variety of chromatography techniques, molecular biology techniques to engineer novel protein constructs for stabilizing and studying weak protein-protein interactions, and various biochemical and biophysical assays of studying protein-protein interactions and enzyme kinetics, including structure-function analysis, pull-down assays, actin polymerization assay, isothermal titration calorimetry, chemical crosslinking, fluorescence-based assays, single molecule fluorescence microscopy, mass spectrometry, NMR, X-ray crystallography, and cryo-EM. As an integral part of research activities, the position also involves writing lab protocols, SOPs, and manuscripts, attending seminars, communicating with collaborators by mails, emails, and on-line meetings, and reporting results in weekly lab meetings as well as local and national conferences.
2) Management (25%) - In addition to research, the position involves miscellaneous types of lab responsibilities, which may include ordering supplies and chemicals, making common lab reagents, maintaining tissue culture and equipment, maintaining laboratory safety, organization, and efficiency, supervising and training undergraduate and graduate students, and training new laboratory staff on standard laboratory procedures.
3) Other (5%) - There may be other duties assigned by the PI where they are needed

This position is an initial term of one year with the opportunity to renew based on performance and funding.

Required Minimum Qualifications:

 Ph.D. degree in biochemistry or related disciplines.

Preferred Qualifications:

• Expertise in purifying and reconstituting large protein complexes from bacterial and eukaryotic cells.
• Expertise in molecular cloning, enzyme kinetics, biophysics, and structural biology.
•  Prior experience in studying proteins related to the actin cytoskeleton.

Proposed Start Date:
August 1, 2022

Proposed End Date or Length of Term:
July 31, 2023

Number of Months Employed Per Year:
12 Month Work Period

Time Type:
Full time

Application Instructions:

To apply for this position, please click on “Apply” and complete the Employment Application. Please be prepared to enter or attach the following:
1) Resume/Curriculum Vitae
2) Letter of Application/Cover Letter
3) Contact Information for Three References
If you have questions regarding this application process, please email employment@iastate.edu or call 515-294-4800 or Toll Free: 1-877-477-7485.
Why Choose ISU?
Iowa State University is committed to fostering a workplace of belonging, where diversity is celebrated and equity is a core value. Our Iowa State Postdocs enjoy comprehensive health and work life benefits, including medical and dental; as well as:
• Retirement benefits including defined benefit and defined contribution plans;
• Generous vacation, holiday, and sick time and leave plans;
• Onsite childcare (Ames, Iowa);
• Flexible Spending Accounts;
• Various voluntary benefits and discounts
• Employee Assistance Program;
• Wellbeing Program.

Original Posting Date:
July 7, 2022

Posting Close Date:
July 14, 2022

Job Requisition Number:
R8941